The Association between Type-2 Diabetes Duration and Major Adverse Cardiac Events after Percutaneous Coronary Intervention

نویسندگان

چکیده

Background. Diabetes is an independent risk factor for coronary artery disease and portends adverse prognosis in diabetic patients undergoing percutaneous intervention (PCI) compared to nondiabetic patients. Few studies are currently available regarding the relationship between diabetes duration major cardiac events (MACEs) post-PCI. This study aimed at assessing association after PCI. Methods. A total of 302 cases elective PCI with drug-eluting stent (DES) deployment or transluminal angioplasty (PTCA) using a drug-coated balloon (DCB) were prospectively studied. We divided into three groups based on duration: <5 years group ( n = 165 ), 5–10 years’ id="M2"> 72 ≥10 id="M3"> 65 ). Angiographic clinical follow-up conducted 12 months procedures all any given time during when needed. Results. significantly higher rate myocardial infarction (MI) longest (7.7% vs. 0% 0.6%, id="M4"> P 0.001 ) was observed shorter duration. Repeat revascularization found be >10-year than it (23.1% 19.4% 9.10%, id="M5"> 0.03 After adjustment confounding factors, longer remained predictor MI (hazard ratio (HR): 5.525, confidence interval (CI): 1.273-23.978, id="M6"> 0.022 repeat (HR: 1.608, CI: 1.058-2.443, id="M7"> 0.026 related progression nontreated lesions (De novo 20% 18% 7.3%, id="M8"> 0.009 previously treated (target lesion (TLR) 3% 1.3% 2%, id="M9"> 0.774 However, all-cause mortality not different among (3.1% 5.6% id="M10"> 0.06 , HR: 2.403, 0.464-12.436, id="M11"> 0.293 Conclusion. associated significant differences intervention; portended rates MACEs 12-month follow-up.

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ژورنال

عنوان ژورنال: Journal of diabetes research

سال: 2021

ISSN: ['2314-6753', '2314-6745']

DOI: https://doi.org/10.1155/2021/7580486